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Pharmacology (Drug Notes)PARACETAMOL (Acetaminophen)

PARACETAMOL (Acetaminophen)

Classification, Uses, Dosages, Common Side Effects, Generic Name and Brand Name

PARACETAMOL  (Acetaminophen)

CLASSIFICATION: Analgesics and Antipyretics

USES:

It is used for treating pain and fever. It is mainly used as a mild moderate pain reliever.

Generally it can be taken orally. Rectally or intravenously can be given upon Physician’s advice.

DOSAGES:

Adult Paracetamol Dose for Fever:

325 to 650 mg every 4 to 6 hours or 1000 mg every 6 to 8 hours orally

Paracetamol 500mg tablets: Two 500 mg tablets orally every 4 to 6 hours

Adult Paracetamol Dose for Pain:

325 to 650 mg every 4 to 6 hours or 1000 mg every 6 to 8 hours orally.

Paracetamol 500mg tablets: Two 500 mg tablets orally every 4 to 6 hours

Pediatric Dose for Fever:

Oral:

<=1 month: 10 to 15 mg/kg/dose every 6 to 8 hours as needed.

>1 month to 12 years: 10 to 15 mg/kg/dose every 4 to 6 hours as needed (Maximum: 5 doses in 24 hours)

Fever: 4 months to 9 years: as per physician guidance

>=12 years: 325 to 650 mg every 4 to 6 hours or 1000 mg every 6 to 8 hours.

Pediatric Dose for Pain:

Oral:

<=1 month: 10 to 15 mg/kg/dose every 6 to 8 hours as needed.

>1 month to 12 years: 10 to 15 mg/kg/dose every 4 to 6 hours as needed (Maximum: 5 doses in 24 hours)

Fever: 4 months to 9 years: as per physician’s guidance


>=12 years: 325 to 650 mg every 4 to 6 hours or 1000 mg every 6 to 8 hours.

NOTE: Dosages can be given or taken as per physician’s instructions and guidance that depends upon the patient’s health condition

COMMON SIDE EFFECTS

If  Paracetamol is taken with right guidance and right dosage there won’t be any side effects. In case if it is taken in overdose there will be serious side effects that are given below;

Serious side effects are

  • Hives
  • Difficulty in breathing
  • Swelling in lips, face, tongue, or throat
  • Loss of appetite
  • Nausea
  • Stomach pain
  • Dark urine
  • Jaundice
  • Bloody or clay colored stools
  • Diarrhea
  • Liver damage
  • Skin allergies
  • Asthma

INTERACTIONS:

Drugs that may interact with ibuprofen paracetamol include:

Few drugs that can interact with Paracetamol or acetaminophen are given below:

  • Busulfan
  • Lomitapide
  • Warfarin
  • Imatinib
  • Flibanserin
  • Daclizumab
  • Tetracaine
  • Lixisenatide
  • Mipomersen
  • Cyanide antidote kit
  • Ephinephrine
  • Alcohol (Ethanol)
  • Alcohol 5% with Dextrose 5%
  • Alcohol and Dextrose injection USP
  • Amyl Nitrate/ Sodium Nitrate
  • Prelocaine
  • Leflunomide
  • Teriflunomide
  • Lidocaine tropical

GENERIC NAME: acetaminophen

BRAND NAMES: Tylenol, calpol, panadol, paramol, paracet, Excedrin, paracip, cetamol, crocin, dolo, dolex, dolorol, metacin, pain relief, pamol, parol, panado, panamax,  paramed, uphamol

PARACETAMOL  (Acetaminophen)
Classification, Uses, Dosages, Common Side Effects, Generic Name and Brand Name

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