INVESTIGATIONS IN PSYCHIATRY Leave a Comment / Psychiatric Nursing / By nurseinfo.in INVESTIGATIONS IN PSYCHIATRYInvestigations are useful to detect alteration in biologic function and to screen for medical disorders causing psychiatric symptoms. Routine Investigations A complete hemogram (total and differential blood count, hemoglobin, ESR) and urinalysis are the basic routine tests. Leucopenia and agranulocytosis are associated with certain medications (Clozapine). Treatment with lithium and neuroleptic malignant syndrome are often associated with leukocytosis.Renal function tests: Treatment with lithiumLiver function tests: For all alcoholic patients treatment with carbamazepine, valproate and benzodiazepinesSerum electrolytes: Dehydration, treatment with carbamazepine, antipsychotics, lithiumBlood glucose: Routine screen above 35 years ageThyroid function test: Depression, treatment with lithium and carbamazepineElectrocardiogram (ECG): Above 35 years of age, treatment with lithium, antidepressants, ECT, antipsychoticsHIV testing: IV drug users suggestive sexual history, AIDS, dementiaVDRL: Suggestive sexual historySerum CPK: Neuroleptic malignant syndrome (markedly increased levels)Chest X-ray: Before treatment with ECTDrug level estimation: Drug levels are indicated to test for therapeutic blood levels, for toxic blood levels and for testing drug compliance. Examples are lithium (0.6 – 1.6 mEq/L), carbamazepine (6-12 mg/mL), valproate (50-100 mg/mL), haloperidol (8-18 ng/mL), tricyclic antidepressants (Imipramine 200-250 ng/mL, nortriptyline 50-150 ng/mL), benzodiazepines, barbiturates. Electrophysiological Tests Electroencephalogram (EEG): Measures brain electrical activity, identifies dysrhythmias and asymmetries, used in the diagnosis of seizures, dementia, neoplasm, stroke, metabolic or degenerative disease. Polysomnography/sleep studies: Used in the diagnosis of sleep disorders and seizures. Brain Imaging Tests (Cranial) Computed tomography (CT) scan: Measures accuracy of brain structure to detect possible lesions, abscesses, areas of infarction or aneurysm. CT scan also identifies various anatomic differences in patients with schizophrenia, organic mental disorder and bipolar disorder.Magnetic resonance imaging (MRI) scan: Measures the anatomic and biochemical status of various segments of the brain; detects brain edema, ischemia, infection, neoplasm, trauma and other changes such as demyelination used in the diagnosis of dementia, to detect morphological changes in schizophrenia patients.Other tests are positron emission tomography (PET). Neuroendocrine Tests Commonly used neuroendocrine tests are dexamethasone suppression test, TRH stimulation test, serum prolactin levels, serum 17-hydroxycorticosteriod, serum melatonin levels. Genetic tests Cytogenetic work-up is advised in some cases of mental retardation. INVESTIGATIONS IN PSYCHIATRY Post navigation ← Previous PostNext Post → Leave a Comment Cancel Reply Your email address will not be published. Required fields are marked *Type here..Name* E-mail* WebsiteSave my name, email, and website in this browser for the next time I comment.