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Pharmacology (Drug Notes)Dexamethasone DRUG

Dexamethasone DRUG

DEXAMETHASONE – Classification, uses, dosages, common side effects, interaction, generic and brand name

CLASSIFICATION: Corticosteroid, Glucocorticoid

USES:

It is used for treating rheumatic problems, skin diseases, allergies, asthma, chronic obstructive lung disease, brain swelling, eye pain, tuberculosis along with antibiotics.

It can be taken orally, through injection or intravenously.

DOSAGES:

Adult dosage (18 years up to 60 years)

0.75–9 mg (depends on the doctor advice)

Pediatric (1–17 years)

0.02–0.3 mg per kilogram of body weight per day (depends on the doctor advice)

NOTE: Dosages can be given or taken as per physician’s instructions and guidance that depends upon the patient’s health condition

COMMON SIDE EFFECTS

Mild side effects are

  • Dizziness
  • Edema
  • Nausea
  • Mood swings
  • Vomiting
  • Headache
  • Stomach upset
  • High blood pressure
  • Tiredness
  • Anxiety
  • Increase in blood glucose level

Serious Side effects (rarely occurs) are

  • Black stools
  • Blood in stool or urine
  • Bleeding
  • Bruising
  • Swelling throughout the body
  • Abdomen bloating
  • Frequent Infections
  • Euphoria
  • Allergies
  • Heart failure
  • Stomach ulcer
  • Osteoporosis

INTERACTIONS:

Drugs(to name a few) that may interact with dexamethasone include:

  • Voriconazole
  • Ketoconazole
  • Amphotericin B
  • Erythromycin
  • Rivaroxaban
  • Warfarin
  • Cholestyramine
  • Aminoglutethimide
  • Metformin
  • Exenatide
  • Pramlintide
  • Insulin
  • Glipizide
  • Glimepiride
  • Canagliflozin
  • Rosiglitazone
  • Bumetanide
  • Phenytoin
  • Carbamazepine
  • Digoxin
  • Oral contraceptives
  • Ritonavir
  • Maraviroc
  • Aspirin
  • Ibuprofen
  • Rifabutin
  • Isoniazid
  • Cyclosporine
  • Smallpox, chickenpox, typhoid (live vaccines)

GENERIC NAME: dexamethasone

BRAND NAME: Baycadron, Decadron, Dexamethasone Intensol, DexPak, TaperDex, Zema-Pak, ZoDex, Zonacort, Dexasone

DEXAMETHASONE Classification, uses, dosages, common side effects, interaction, generic and brand name
DEXAMETHASONE – Classification, uses, dosages, common side effects, interaction, generic and brand name
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