INSULIN (Regular) or HUMAN INSULIN

INSULIN  (Regular) or HUMAN INSULIN

Classification, uses, dosages, common side effects, interaction, generic and brand name

CLASSIFICATION: Protein 

USES:

It is used for treating type-1 diabetes, type-2 diabetes, gestational diabetes, diabetic ketoacidosis, hyperosmolar hyperglycemic states.  High blood potassium levels are also treated using insulin along with glucose.

It can be taken or given through injection under skin. In some cases some forms of insulin are used by injection into a vein or muscle.

DOSAGES:

Dosage calculation formula:

Insulin Dosage Calculation Formula

                         

  • TR = target rate (measured as mg/dL or mmoI/L)
  • CF = corrective factor
  • KF = carbohydrate factor
  • Blood glucose (measured as mg/dL or mmoI/L)

TR, CF, KF should be set by a physician or clinical pharmacist.

Regular human insulin is available in two forms or concentrations:

  • 100 units of insulin per mL (U-100)
  • 500 units of insulin per mL (U-500)

All dosages and units has to be given as per doctor’s advice.

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NOTE: Dosages can be given or taken as per physician’s instructions and guidance that depends upon the patient’s health condition

COMMON SIDE EFFECTS

Mild side effects are

  • Arms and legs swelling
  • Dizziness
  • Fast heart rate
  • Weight gain
  • Blurred vision
  • Anxiety
  • Mood swings
  • Hunger
  • Redness
  • Itching

Serious Side effects (rarely occurs) are

  • Hypoglycemia
  • Delirium
  • Fatigue
  • Lack of coordination
  • Impaired vision
  • Seizures
  • Loss of consciousness
  • Numbness in tongue or lips

INTERACTIONS:

Drugs(to name a few) that may interact with insulin (regular) include:

Check with your doctor for better understanding about the interactions with these drugs before taking them along with insulin (regular)

  • Rosiglitazone
  • Thiazolidinediones
  • Pramlintide
  • MAOIs
  • Fluoxetine
  • Lisinopril
  • Losartan
  • Valsartan
  • Metoprolol
  • Diuretics
  • Propranolol
  • Niacin
  • Disopyramide
  • Aspirin
  • Pentoxifylline
  • Corticosteroidsclozapine
  • Isoniazid
  • Pentamidine
  • Glucagon
  • Somatropin
  • reserpine
  • Hormones – estrogens, progesterone
  • Ritonavir

GENERIC NAME: insulin/NPH insulin  

BRAND NAME: Humulin R, Novolin R, Humulin R U-500 (Concentrated), Myxredlin, human mixtard, human mixact, human mixtard 50

INSULIN (Regular) or HUMAN INSULIN Classification, uses, dosages, common side effects, interaction, generic and brand name
INSULIN (Regular) or HUMAN INSULIN Classification, uses, dosages, common side effects, interaction, generic and brand name

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